Filling wrinkles with fat
Written and reviewed by Dr Bernard Hayot, ophthalmologist, RPPS 10003926226.

Filling wrinkles with fat
The use of autologous fat to fill wrinkles is a significant advance in aesthetic medicine and reconstructive surgery. Dr Hayot explains the innovative methods that use the body’s own fat to restore facial volume lost with age and to treat wrinkles, as well as the way techniques for refining fat have evolved to allow more delicate applications.
The role of fat injections in filling wrinkles
Injecting fat into the face to treat wrinkles is a technique that has evolved considerably, and today offers a wide range of options for treating different kinds of wrinkles and loss of volume. Thanks to advances in the preparation of fat and to innovations such as nanofat, practitioners can offer their patients tailor-made solutions with natural, long-lasting results. This comprehensive approach not only fills wrinkles but also contributes to skin regeneration, which underlines the growing importance of regenerative medicine in the aesthetic field.
Which areas can be treated with fat injections?
For years, facial fat injection has been used to restore volume lost to ageing. The results are often very impressive, with a natural look, a treatment that lasts well and fat that integrates perfectly into the various layers of the face. The method not only fills hollow areas but also gives the face a more youthful, rested appearance.
How do fat injections work against wrinkles?
The evolution of fat preparation techniques has been crucial to the development of new applications in the treatment of wrinkles. By carefully removing all fibrous cells and separating the fat cells, it became possible to pass fat through ever finer cannulas, and even through needles. This technical advance opened the way to injecting fat into deep wrinkles and, later, into finer, more superficial ones.
- Treating wrinkles with broken or emulsified fat: to treat fine, superficial wrinklessuch as perioral wrinkles or fine lines on the cheeks, the fat is slightly broken down or emulsified. This changes the density and fineness of the fat so that it can be injected with even greater precision, which makes it possible to treat even the most delicate wrinkles effectively.
- Nanofat, the notable advance in regenerative medicine: Nanofat techniques are used for very fine wrinkles and breaks in the skin, such as the perioral wrinkles responsible for the barcode appearance around the lips. This is a major advance in which, instead of fat cells, stem cells and growth factors are extracted from fat that has been broken down and emulsified through several filters. These stem cells have the potential to regenerate the skin significantly, with excellent results in improving skin quality. This approach lies at the heart of regenerative medicine, which aims to restore the function and appearance of damaged or ageing tissue.
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