Micro-lipofilling of the nasolabial folds
Written and reviewed by Dr Bernard Hayot, ophthalmologist, RPPS 10003926226.

What is the nasolabial fold?
The nasolabial fold is an expression line that deepens as the face ages and with repeated facial expressions, smiles and chewing. Its depth also depends on each person’s genetic inheritance and on the particular features of their face.
Nasolabial folds, also known as “smile lines”, can today only be treated effectively by aesthetic medicine and surgery.
Creams and make-up are not satisfactory anti-ageing measures for this break in the skin, which grows deeper over time. Hyaluronic acid injections, fractional laser sessions and fat lipofilling techniques, on the other hand, have proved their worth in filling facial wrinkles.
Laser, hyaluronic acid or lipofilling: which anti-ageing technique is best?
The choice of wrinkle-filling method depends on each patient’s indication. Allergies, predispositions and apprehensions also influence the choice made by the oculoplastic surgeon.
Fractional laser treatment:
fractional laser treatment reduces fine lines and wrinkles in just a few sessions. Light energy is used to resurface the skin and significantly rejuvenate the whole area treated. The laser can also correct changes in the appearance of the skin, such as dilated pores, a dull complexion or acne scars.
Discover the benefits of fractional laser
Hyaluronic acid injections
Injections of highly cross-linked hyaluronic acid, such as Juvederm Ultra 2, temporarily fill the nasolabial fold. Expect the product to last 12 to 18 months: hyaluronic acid is resorbable and naturally biodegradable.
Discover the benefits of hyaluronic acid injections
Micro-lipofilling of facial wrinkles
Micro-lipofilling involves taking fat from the patient’s abdomen or inner knees. This fat, centrifuged and purified, is then used as a filler to treat the nasolabial fold and all other expression lines of the face, such as crow’s feet, marionette lines and glabellar lines.
Discover the benefits of lipofilling and lipostructure
Lipofilling of the nasolabial folds: the clear winner
Although Dr Bernard Hayot, oculoplastic surgeon in Paris, performs eyelid and oculoplastic surgery, he increasingly turns to fat injections: “Lipofilling is a safe and effective technique whose results last longer than hyaluronic acid injections. Safe and with a very limited risk of rejection, this principle of fat autografting allows us to restore the facial volume lost over time. My patients’ faces are full of youth again,” says Dr Hayot.
For more information on filling the nasolabial folds, make an appointment with Dr Bernard Hayot.
This page is for information. It does not replace a consultation: every situation is judged on examination.